Prostate cancer stage 3 treatment
Subjects must meet all of the following criteria to be enrolled in this study: 1. Male aged 21 years or older. Ability to provide signed informed consent and willingness to comply with protocol requirements.
Emory University Rövid összefoglaló This phase II trial investigates whether proton radiation therapy directed to the prostate tumor and nearby lymph nodes, is an effective way to treat patients with high-risk prostate cancer who are receiving radiation therapy, and if it will result in fewer gastrointestinal and genitourinary side effects. Proton beam therapy is a new type of radiotherapy that directs multiple beams of protons positively charged subatomic particles at the tumor target, where they deposit the bulk of their energy with essentially no residual radiation beyond the tumor.
By reducing the exposure of the healthy tissues and organs to radiation in the treatment of prostate cancer, proton therapy has the potential to better spare healthy tissue and reduce the side effects of radiation therapy.
The information learned from this study may also help researchers to learn more about proton therapy for the treatment prosztata szűrés vérből patients with prostate cancer. To assess the feasibility of extended-field proton irradiation of high-risk prostate. To demonstrate safety of proton therapy followed by high dose rate HDR boost.
To determine patient-reported outcomes PROs of toxicity. Patients may receive a high-dose rate brachytherapy boost.
After completion of study treatment, patients are followed up at 1, 3, 6, 9 and 12 months, and 1. Átfogó állapot.